molecular docking - Aneknowledge.com

Integrative bioinformatics and chemotactic insights into p-nitrophenol bioremediation by halotolerant aquatic Pseudomonas sp. strain PNPBRP5(2).

Halotolerant Pseudomonas Strain Shows Breakthrough Potential for p-Nitrophenol Bioremediation in Aquatic Environments

A newly isolated Pseudomonas sp. strain PNPBRP5(2) efficiently degraded 98% of p-nitrophenol (PNP) within 60 hours, demonstrating strong chemotactic and enzymatic activity for eco-friendly bioremediation of toxic aquatic pollutants.

Aneknowledge October 24, 2025

Medicinal fungi-derived secondary metabolites as potential inhibitors of DNA polymerase beta: a computational approach against liver cancer.

Emerging Science Health Molecular Biology

Medicinal Mushrooms Show Promise in Liver Cancer Treatment Through DNA Repair Enzyme Inhibition

A computational study identifies medicinal mushroom compounds that inhibit DNA polymerase β—an enzyme linked to tumor progression in hepatocellular carcinoma. The lead compound, Phellibaumin A, exhibits strong binding affinity, favorable pharmacokinetics, and low toxicity, suggesting a potential new route for liver cancer therapy.

Aneknowledge October 14, 2025

1-acetyl-4-(hydroxylphenyl) piperazine inhibits biofilm formation in ESKAPE pathogens Klebsiella pneumoniae and Acinetobacter baumannii.

Emerging Science Microbiology Natural Products

1-Acetyl-4-(Hydroxylphenyl) Piperazine: A Promising Weapon Against Biofilm-Forming Superbugs

Discover how 1-acetyl-4-(hydroxylphenyl) piperazine (AHPP) disrupts biofilm formation in multidrug-resistant ESKAPE pathogens like Klebsiella pneumoniae and Acinetobacter baumannii, paving the way for next-gen antimicrobial therapies.

Aneknowledge October 4, 2025